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1

Cadmium carcinogenesis in review

Michael P Waalkes

Journal:

Journal of Inorganic Biochemistry

Year:

2000

Language:

english

File:

PDF, 78 KB

english, 2000

2

Aberrant cytokeratin expression during arsenic-induced acquired malignant phenotype in human HaCaT keratinocytes consistent with epidermal carcinogenesis

Yang Sun, Jingbo Pi, Xueqian Wang, Erik J. Tokar, Jie Liu, Michael P. Waalkes

Journal:

Year:

2009

Language:

english

File:

PDF, 1.24 MB

english, 2009

3

Induction of Proliferative Lesions of the Uterus, Testes, and Liver in Swiss Mice Given Repeated Injections of Sodium Arsenate: Possible Estrogenic Mode of Action

Michael P. Waalkes, Larry K. Keefer, Bhalchandra A. Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

2000

Language:

english

File:

PDF, 1.02 MB

english, 2000

4

Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

Jingbo Pi, Bhalchandra A. Diwan, Yang Sun, Jie Liu, Wei Qu, Yuying He, Miroslav Styblo, Michael P. Waalkes

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 985 KB

english, 2008

5

Evaluation of DNA damage in patients with arsenic poisoning: urinary 8-hydroxydeoxyguanine

Hiroshi Yamauchi, Yoshito Aminaka, Katsumi Yoshida, Guifan Sun, Jingbo Pi, Michael P Waalkes

Journal:

Toxicology and Applied Pharmacology

Year:

2004

Language:

english

File:

PDF, 277 KB

english, 2004

6

Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation

Lamia Benbrahim-Tallaa, Robert A. Waterland, Miroslav Styblo, William E. Achanzar, Mukta M. Webber, Michael P. Waalkes

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 417 KB

english, 2005

7

The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic

Verne Tsang, Rebecca C. Fry, Mihai D. Niculescu, Julia E. Rager, Jesse Saunders, David S. Paul, Steven H. Zeisel, Michael P. Waalkes, Miroslav Stýblo, Zuzana Drobná

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.00 MB

english, 2012

8

Arsenic-induced cancer cell phenotype in human breast epithelia is estrogen receptor-independent but involves aromatase activation

Xu, Yuanyuan, Tokar, Erik J., Waalkes, Michael P.

Journal:

Archives of Toxicology

Year:

2014

Language:

english

File:

PDF, 1.58 MB

english, 2014

9

Arsenic Exposure Transforms Human Epithelial Stem/Progenitor Cells into a Cancer Stem-like Phenotype

Erik J. Tokar, Bhalchandra A. Diwan and Michael P. Waalkes

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 2.28 MB

english, 2010

10

Chronic Exposure of Renal Stem Cells to Inorganic Arsenic Induces a Cancer Phenotype

Tokar, Erik J., Person, Rachel J., Sun, Yang, Perantoni, Alan O., Waalkes, Michael P.

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 485 KB

english, 2013

11

Cancer in experimental animals exposed to arsenic and arsenic compounds

Tokar, Erik J., Benbrahim-Tallaa, Lamia, Ward, Jerrold M., Lunn, Ruth, Sams, Reeder L., Waalkes, Michael P.

Journal:

Critical Reviews in Toxicology

Year:

2010

Language:

english

File:

PDF, 818 KB

english, 2010

12

INDUCTION OF c- myc AND c- jun PROTO-ONCOGENE EXPRESSION IN RAT L6 MYOBLASTS BY CADMIUM IS INHIBITED BY ZINC PREINDUCTION OF THE METALLOTHIONEIN GENE

Abshire, Michael K., Buzard, Gregory S., Shiraishi, Noriyuki, Waalkes, Michael P.

Journal:

Journal of Toxicology and Environmental Health

Year:

1996

Language:

english

File:

PDF, 13.93 MB

english, 1996

13

Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells

Person, Rachel J., Olive Ngalame, Ntube N., Makia, Ngome L., Bell, Matthew W., Waalkes, Michael P., Tokar, Erik J.

Journal:

Toxicology and Applied Pharmacology

Year:

2015

Language:

english

File:

PDF, 852 KB

english, 2015

14

Recruitment of Normal Stem Cells to an Oncogenic Phenotype by Noncontiguous Carcinogen-Transformed Epithelia Depends on the Transforming Carcinogen

Xu, Yuanyuan, Tokar, Erik J., Person, Rachel J., Orihuela, Ruben G., Ngalame, Ntube O., Waalkes, Michael P.

Journal:

Environmental Health Perspectives

Year:

2013

Language:

english

File:

PDF, 1.54 MB

english, 2013

15

Mitigation of arsenic-induced acquired cancer phenotype in prostate cancer stem cells by miR-143 restoration

Ngalame, Ntube N.O., Makia, Ngome L., Waalkes, Michael P., Tokar, Erik J.

Journal:

Toxicology and Applied Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.25 MB

english, 2015

16

Lead as a carcinogen: Experimental evidence and mechanisms of action

Ellen K. Silbergeld, Michael Waalkes, Jerry M. Rice

Journal:

American Journal of Industrial Medicine

Year:

2000

Language:

english

File:

PDF, 156 KB

english, 2000

17

Lead effects on protamine–DNA binding

Betzabet Quintanilla-Vega, Dennis Hoover, Wojciech Bal, Ellen K. Silbergeld, Michael P. Waalkes, Larry D. Anderson

Journal:

American Journal of Industrial Medicine

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

18

Genetic events associated with arsenic-induced malignant transformation: applications of cDNA microarray technology

Hua Chen, Jie Liu, Bruce A. Merrick, Michael P. Waalkes

Journal:

Molecular Carcinogenesis

Year:

2001

Language:

english

File:

PDF, 209 KB

english, 2001

19

Effects of exogenous cysteine on inorganic and organic arsenicals-induced cytolethality

Teruaki Sakurai, Chikara Kojima, Michael P. Waalkes, Seiichiro Himeno

Journal:

Applied Organometallic Chemistry

Year:

2006

Language:

english

File:

PDF, 188 KB

english, 2006

20

Cytotoxicological aspects of the organic arsenic compound arsenobetaine in marine animals

Chikara Kojima, Teruaki Sakurai, Masayuki Ochiai, Hidetoshi Kumata, Wei Qu, Michael P. Waalkes, Kitao Fujiwara

Journal:

Applied Organometallic Chemistry

Year:

2002

Language:

english

File:

PDF, 148 KB

english, 2002

21

Cadmium-induced malignant transformation in rat liver cells: Role of aberrant oncogene expression and minimal role of oxidative stress

Wei Qu, Bhalchandra A. Diwan, Jeffrey M. Reece, Carl D. Bortner, Jingbo Pi, Jie Liu, Michael P. Waalkes

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 549 KB

english, 2005

22

Low level, long-term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: Potential role in skin co-carcinogenesis

Jingbo Pi, Yuying He, Carl Bortner, Jianli Huang, Jie Liu, Tong Zhou, Wei Qu, Susan L. North, Kazimierz S. Kasprzak, Bhalchandra A. Diwan, Colin F. Chignell, Michael P. Waalkes

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 243 KB

english, 2005

23

Hypersusceptibility to cisplatin carcinogenicity in metallothionein-I/II double knockout mice: Production of hepatocellular carcinoma at clinically relevant doses

Michael P. Waalkes, Jie Liu, Kazimierz S. Kasprzak, Bhalchandra A. Diwan

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

24

Acquisition of apoptotic resistance in cadmium-induced malignant transformation: Specific perturbation of JNK signal transduction pathway and associated metallothionein overexpression

Wei Qu, Richard Fuquay, Teruaki Sakurai, Michael P. Waalkes

Journal:

Molecular Carcinogenesis

Year:

2006

Language:

english

File:

PDF, 517 KB

english, 2006

25

Effects of magnesium acetate on the toxicity of nickelous acetate in rats

Kazimierz S. Kasprzak, Michael P. Waalkes, Lionel A. Poirier

Journal:

Year:

1986

Language:

english

File:

PDF, 653 KB

english, 1986

26

Effect of L-ascorbic acid tretreatment on cadmium toxicity in the male Fischer (F344/NCr) rat

Noriyuki Shiraishi, Hiroshi Uno, Michael P. Waalkes

Journal:

Year:

1993

Language:

english

File:

PDF, 1022 KB

english, 1993

27

Metallothionein gene expression in testicular interstitial cells and liver of rats treated with cadmium

Ilda Melo Mckenna, Robert M. Bare, Michael P. Waalkes

Journal:

Year:

1996

Language:

english

File:

PDF, 1006 KB

english, 1996

28

Mechanisms underlying arsenic carcinogenesis: hypersensitivity of mice exposed to inorganic arsenic during gestation

Michael P Waalkes, Jie Liu, Jerrold M Ward, Bhalchandra A Diwan

Journal:

Year:

2004

Language:

english

File:

PDF, 100 KB

english, 2004

29

Strain differences of cadmium-induced hepatotoxicity in Wistar–Imamichi and Fischer 344 rats: involvement of cadmium accumulation

Hideaki Shimada, Yasutaka Takamure, Akinori Shimada, Akira Yasutake, Michael P. Waalkes, Yorishige Imamura

Journal:

Year:

2004

Language:

english

File:

PDF, 241 KB

english, 2004

30

Nitric oxide and chemically induced hepatotoxicity: beneficial effects of the liver-selective nitric oxide donor, V-PYRRO/NO

Jie Liu, Michael P. Waalkes

Journal:

Year:

2005

Language:

english

File:

PDF, 132 KB

english, 2005

31

Arsenicals in maternal and fetal mouse tissues after gestational exposure to arsenite

Vicenta Devesa, Blakely M. Adair, Jie Liu, Michael P. Waalkes, Bhalchandra A. Diwan, Miroslav Styblo, David J. Thomas

Journal:

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

32

Impact of life stage and duration of exposure on arsenic-induced proliferative lesions and neoplasia in C3H mice

Gene J. Ahlborn, Gail M. Nelson, Rachel D. Grindstaff, Michael P. Waalkes, Bhalchandra A. Diwan, James W. Allen, Kirk T. Kitchin, R. Julian Preston, Araceli Hernandez-Zavala, Blakely Adair, David J. T

Journal:

Year:

2009

Language:

english

File:

PDF, 904 KB

english, 2009

33

Transcriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic

Gail M. Nelson, Gene J. Ahlborn, James W. Allen, Hongzu Ren, J. Christopher Corton, Michael P. Waalkes, Kirk T. Kitchin, Bhalchandra A. Diwan, Geremy Knapp, Don A. Delker

Journal:

Year:

2009

Language:

english

File:

PDF, 1.17 MB

english, 2009

34

Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice

Jie Liu, Yaping Liu, Sultan M Habeebu, Michael P Waalkes, Curtis D Klaassen

Journal:

Year:

2000

Language:

english

File:

PDF, 420 KB

english, 2000

35

Cyproterone acetate induces a cellular tolerance to cadmium in rat liver epithelial cells involving reduced cadmium accumulation

Masufumi Takiguchi, Nathan J. Cherrington, Dylan P. Hartley, Curtis D. Klaassen, Michael P. Waalkes

Journal:

Year:

2001

Language:

english

File:

PDF, 200 KB

english, 2001

36

Multidrug-resistance mdr1a/1b double knockout mice are more sensitive than wild type mice to acute arsenic toxicity, with higher arsenic accumulation in tissues

Jie Liu, Yaping Liu, Douglas A Powell, Michael P Waalkes, Curtis D Klaassen

Journal:

Year:

2002

Language:

english

File:

PDF, 396 KB

english, 2002

37

The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen-induced nephrotoxicity in mice

Chengxiu Li, Jie Liu, Joseph E. Saavedra, Larry K. Keefer, Michael P. Waalkes

Journal:

Year:

2003

Language:

english

File:

PDF, 335 KB

english, 2003

38

Testosterone pretreatment mitigates cadmium toxicity in male C57 mice but not in C3H mice

Hideaki Shimada, Robert M. Bare, James F. Hochadel, Michael P. Waalkes

Journal:

Year:

1997

Language:

english

File:

PDF, 967 KB

english, 1997

39

Lack of correlation between the inducibility of metallothionein mRNA and metallothionein protein in cadmium-exposed rodents

R. Rita Misra, Kimberly A. Crance, Robert M. Bare, Michael P. Waalkes

Journal:

Year:

1997

Language:

english

File:

PDF, 940 KB

english, 1997

40

Suppression of Kupffer cell function prevents cadmium induced hepatocellular necrosis in the male Sprague-Dawley rat

John-Michael Sauer, Michael P Waalkes, Stephen B Hooser, Robert K Kuester, Charlene A McQueen, I.Glenn Sipes

Journal:

Year:

1997

Language:

english

File:

PDF, 356 KB

english, 1997

41

Evaluation of the direct genotoxic potential of cadmium in four different rodent cell lines

R.Rita Misra, George T Smith, Michael P Waalkes

Journal:

Year:

1998

Language:

english

File:

PDF, 176 KB

english, 1998

42

Lack of carcinogenicity of cadmium chloride in female Syrian hamsters

Michael P Waalkes, Sabine Rehm

Journal:

Year:

1998

Language:

english

File:

PDF, 69 KB

english, 1998

43

Expression Profiling of Human Keratinocyte Response to Ultraviolet A: Implications in Apoptosis

He, Yu-Ying, Huang, Jian-Li, Sik, Robert H., Chignell, Colin F., Liu, Jie, Waalkes, Michael P.

Journal:

The Journal of Investigative Dermatology

Year:

2004

Language:

english

File:

PDF, 379 KB

english, 2004

44

Altered apoptotic gene expression and acquired apoptotic resistance in cadmium-transformed human prostate epithelial cells

William E. Achanzar, Mukta M. Webber, Michael P. Waalkes

Journal:

Year:

2002

Language:

english

File:

PDF, 235 KB

english, 2002

45

Estrogen signaling and disruption of androgen metabolism in acquired androgen-independence during cadmium carcinogenesis in human prostate epithelial cells

Lamia Benbrahim-Tallaa, Jie Liu, Mukta M. Webber, Michael P. Waalkes

Journal:

Year:

2007

Language:

english

File:

PDF, 306 KB

english, 2007

46

Early effects of surgery on zinc and metallothionein levels in female rats

Eduardo Brambila, Jose Luis Muñoz-Sánchez, Arnulfo Albores, Michael Waalkes

Journal:

Biological Trace Element Research

Year:

1999

Language:

english

File:

PDF, 542 KB

english, 1999

47

Strain difference of cadmium-induced testicular toxicity in inbred Wistar–Imamichi and Fischer 344 rats

Hideaki Shimada, Rika Narumi, Masaaki Nagano, Akira Yasutake, Michael P. Waalkes, Yorishige Imamura

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 287 KB

english, 2009

48

Methylation status and organization of the metallothionein-I gene in livers and testes of strains of mice resistant and susceptible to cadmium

Mrinal R. Bhave, Mary J. Wilson, Michael P. Waalkes

Journal:

Year:

1988

Language:

english

File:

PDF, 2.08 MB

english, 1988

49

Aberrant DNA methylation and gene expression in livers of newborn mice transplacentally exposed to a hepatocarcinogenic dose of inorganic arsenic

Yaxiong Xie, Jie Liu, Lamia Benbrahim-Tallaa, Jerry M. Ward, Daniel Logsdon, Bhalchandra A. Diwan, Michael P. Waalkes

Journal:

Year:

2007

Language:

english

File:

PDF, 334 KB

english, 2007

50

Early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice

Erik J. Tokar, Bhalchandra A. Diwan, Michael P. Waalkes

Journal:

Year:

2010

Language:

english

File:

PDF, 474 KB

english, 2010